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The diminishing effectiveness of current antibiotic treatments and the challenges associated with vaccine development have encouraged exploration of novel therapeutic strategies to prevent and/or treat NTHi infections

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Likewise, an essential problem with regard to the active (and effective) peptide is the continuous search for new delivery systems and new carriers, and new carriers and delivery systems together, with all standard angiogenic growth factors to improve their efficacy, although they are very extensive and highly sophisticated (for review, see Saghazadeh et al., 2018