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This mechanism is different from acid-suppressing drugs like proton pump inhibitors (PPIs) or H2 blockers, which reduce acid production but do not affect the LES function directly

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Another clinical study clarified that adding RSV (100 mg/day, P.O for 2 months) better improved left ventricular ejection fraction and left ventricular diastolic function in patients with CHD compared with standard treatment alone [199]

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