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We reproduced this potentially reversible response by human adult mature OLs in both dissociated cell culture and microfibre ensheathment assays, using an array of insults implicated in MS pathogenesis including the pro-inflammatory molecules interferon (IFN)- and tumor necrosis factor (TNF)-, the excitatory neutrotransmitter glutamate, and metabolic stress conditions involving nutrient deprivation and low glucose 19,42

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The goal of surgery is to preserve the meniscus by repairing or removing the torn part

in maintenance you inject about every other active day (e.g., Mon/Wed/Fri)

Health-care professionals should have increased awareness about CTS and all its implications

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