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What the Latest Research Reveals Interest in nextgeneration metabolic therapies

GPX4 is an antioxidant enzyme that primarily reduces lipid peroxides, especially lipid hydroperoxides, into their corresponding alcohols, thus protecting cell membranes from oxidative damage [39]

Extension of the CHARMM General Force Field to sulfonyl-containing compounds and its utility in biomolecular simulations

Gao X, Wang XL

RR014B, Takara Bio, Kusatsu, Japan)

Rare variant analysis has revealed that loss-of-function mutations within activating transcription factor 4 (ATF4), a transcription factor responsible for the upregulation of serine synthesis under conditions of serine starvation, are associated with higher risk for PAH, which further suggests serine is closely related PAH