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These compounds increase SIRT1 expression or activity, collectively improving hepatic lipid metabolism, insulin signaling, oxidative stress, autophagy, and inflammatory responses, highlighting their strong multi-target pharmacological potential

In ovarian cancer, a lack of glutamine may induce endoplasmic reticulum stress in cytotoxic T cells, depleting their glutamine transporters and impairing their function

thermophilus is inevitably exposed to various environmental pressures during food production and beverage consumption

These triterpenoids impede inflammation progression by inhibiting cyclooxygenase (COX) and PLA2 activity, blocking the release of cytokines, histamine, and serotonin, and interacting with serine/threonine kinases [299]