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Ankylosing Spondylitis: Ankylosing spondylitis primarily affects the spine and sacroiliac joints, leading to chronic inflammation and pain
A single fasting growth hormone (GH) level is of limited value
People on anticoagulant therapy need medical clearance before using any compound that affects vascular function
Notably, obesity and joint injury remain the most prominent modifiable risk factors, whereas age, sex, and genetic predisposition are considered non-modifiable contributors (Figure 2) (Nedunchezhiyan et al., 2022
Ongoing research is expected to expand the list of TCM-derived metabolites with evidence-based benefits, to optimize their formulations (for example, improving bioavailability of poorly absorbed molecules), and to clarify their roles in practice (whether as adjuncts to standard therapy to address residual risks like inflammation, or as alternatives in specific scenarios such as statin-intolerant patients)