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Paclitaxel, doxorubicin, and vincristine, known as MRP7 or MRP1 substrate drugs, were used as positive controls for different cell lines, and cisplatin as non-substrate for both MRP7 and MRP1 was used as the negative control

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The oxidants involvement in several diseases is well established, however there isnt unanimity about it ( Halliwell and Gutteridge, 1989)

This results in faster collagen remodeling, improved elasticity, and stronger rejuvenation effects