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PD is partly caused by the neurotoxicity of iron accumulation brought on by inadequate or reduced ferroxidase activity of ceruloplasmin [99, 100]

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The methylated variants of pangamic acid, also known as d glucono dimethylamino acetate, a supposedly naturally occurring B vitamin, were synthesized in the 1950s using the chemical diisopropylammonium dichloroacetate (DIPA)

Although DSIP has demonstrated some promise as an antioxidant, antiedemic, and anticonvulsant agent, the research to date has been limited to animal studies, so its uncertain whether desired health outcomes are attainable in humans

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J Allergy Clini Immunol 118:226232 Acknowledgements None