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The study by Honda et al., conducted in 2017, was an open-label, single-arm, multicentre pilot study that evaluated the therapeutic effect of oral glutathione administration (300 mg/day) in patients with NAFLD through the evolution of biochemical indices (ALT) and liver fat levels assessed by VCTE (79)

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These clusters provide the electrons necessary for the reductive cleavage of SAM, generating a 5-deoxyadenosyl radical, which initiates radical mechanisms