The cellular Nrf2 level is quite low in normal unstressed situations, but it substantially increases when exposed to electrophilic compounds or reactive oxygen species (ROS) (Itoh et al., 1997)
doi:10.5402/2013/246737 Martineau AR, Jolliffe DA, Greenberg L, et al
Retinoids can be effective in severe adult psoriasis that does not respond to other therapies, and are sometimes combined with other treatments
When autoimmunity flares, as in other cases of chronic inflammation, antioxidant defenses are weaker
Some of our patients do well with twice a week, so that theres a nice, big recovery gap between sessions
When mitochondrial function is optimized (red light, NAD+), hormones are maintained (HRT, TRT), inflammation is controlled (peptides, HBOT), and cellular repair is supported (growth hormone peptides, sleep optimization) the visible markers of aging (wrinkles, skin thinning, volume loss, hair changes) progress more slowly than they would without intervention