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It is derived from a protein sequence originally identified during research involving gastric proteins, leading scientists to investigate its biological properties under controlled laboratory conditions

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In Everyone (Men and Women): High blood pressure Type 2 diabetes or insulin resistance Central weight gain (especially around the abdomen) Fatty liver disease (NAFLD) Depression, anxiety, irritability Sleep disturbances and fatigue Osteopenia or osteoporosis Weakened immune function Higher risk of heart disease and stroke The effects can also differ by gender

J Pharmacol Exp Ther 1995

This increase was slight and not thought to be clinically significant