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We have also demonstrated that morphine and DAMGO induce different mechanisms of MOPr desensitization in mature neurons of the rat locus coeruleus (LC

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The natural antioxidants, as a result of proper nutritional habits, provide indirect protection by decreasing the production of cytokines and reducing OxS ( Numerous exogenous antioxidant molecules (nutritional antioxidants) have been shown to play an important role in excessive ROS accumulation in organisms