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A large body of evidence indicates that various cellular metabolic pathways such as amino acid, lipid, glucose, and iron metabolism, can promote ferroptosis

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Description & Mechanism AOD9604 is a synthetic peptide derived from the C-terminal fragment (residues 176191) of human growth hormone (hGH), with sequence modifications introduced to enhance stability and research utility

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Alternative repletion strategies have focused on oral administration of GSH precursors (e.g., cysteine and glycine supplementation 9 ), and intravenous administration of GSH, 10 which although promising, is invasive and inconvenient, and therefore unlikely to be a practical solution

On the other hand, one study found that 94 percent of patients experienced adverse reactions, and another trial was halted after a patient died (though it wasnt clear whether the drug caused the death)