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Chronic modulation of growth and repair pathways warrants caution

Assisted reproduction and thyroid autoimmunity: an unfortunate combination

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However, FOXO4-DRI treatment significantly reduced the expression of these detrimental SASP factors and, critically, restored the proliferation of GC-1 spg cells in the co-culture system, as evidenced by CCK-8 assays and PCNA expression, without inducing apoptosis in the spermatogonia