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Although these findings do not conclusively rule out SARS-CoV-2 infection of the CNS, the evidence suggests that it is unlikely and neurological manifestations of infection may be largely due to systemic inflammatory responses to infection, as well as peripheral organ injury

R.Tuakli-WosornuY.SkidmoreE.SilverJ

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For research protocols requiring maximum stability, refrigerated storage within the 28-day window is always preferable to frozen storage

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At the molecular level, lower levels of the sealing claudins-3,5, and7 and more pore-forming claudin-2 were reported (82)