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Studied in models involving nicotinamide N-methyltransferase signaling, methylation-linked metabolism, and metabolic pathway regulation
10.1016/j.redox.2017.12.019 Summary Keywords liver fibrosis, thioacetamide, Nrf2, SIRT1, oxidative stress, remogliflozin Citation ALSuhaymi N, Alsugoor MH, Shokry AA, Fayed HM, Mohamed BMSA, Afifi SM, Esatbeyoglu T, Korany RMS and Elbaset MA (2025) Protective role of remogliflozin against experimental liver fibrosis by activating AMPK/SIRT1/Nrf2 and suppressing NF-B pathways
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Mechanism for antioxidative effects of thiazolidinediones in pancreatic -cells
Furthermore, flow cytometry detected the changes of M1 (CD86 marker) and M2 (CD206 marker) macrophage phenotypes after various treatments