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These micelles, upon visible light activation, formed cross-linked cores that exhibited enhanced in vivo stability and prolonged blood circulation, ultimately leading to greater tumor accumulation

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10.1080/00498254.2023.2270046 246 ZangH.YangQ.LiJ

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Pigmented dark circles stem from melanin accumulation in periorbital skin from chronic sun exposure without adequate protection, post-inflammatory hyperpigmentation from rubbing or allergies, genetic predisposition particularly in darker skin types, or hormonal influences affecting melanocyte activity

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