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This innovative combination not only brightens the skin but also offers profound anti-aging benefits, enhancing skin elasticity and reducing the appearance of wrinkles

Furthermore, heme can drive TNF-- and ROS-mediated necroptosis [225], heme oxygenase 1-dependent ferroptosis [226], and NLRP3 inflammasome-associated pyroptosis [227], which are highly proinflammatory RCDs

Likewise, magnetic mesoporous silica nanoparticles (M-MSNs) were targeted to the HepG2 cells bearing mice where the MSN were externally directed using the electromotive force (EMF) and/or alternating current magnetic force (ACMF), which in combination was found to be most effective [217]

Prez de la Lastra et al., 2021

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J Clin Aesthet Dermatol