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Goc J, Germain C, Vo-Bourgais TKD, Lupo A, Klein C, Knockaert S, et al

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Developmental differences in HO-induced oligodendrocyte cell death: role of glutathione, mitogen-activated protein kinases and caspase 3

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However, respiratory function was found to be impaired in asthma patients characterized by lower selenium levels than control group subjects (246, 249)

This upregulation exhausts intracellular GSH, leading to ROS buildup and oxidative DNA damage that can ultimately generate TP53 mutations, a process that is halted when CHAC1 is knocked down (Wada et al., 2018)