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The Molecular Mechanisms of Iron Metabolism and its Role in Cardiac Dysfunction and Cardioprotection

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54 Based on the above studies, NAC, at a dose of 1200 mg per day, appears to have benefits in patients with NASH, with treatment durations of 48 weeks or more and in combination with metformin

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While this interaction primarily affects dietary B12 absorption rather than injected cyanocobalamin, patients on long-term acid suppression therapy may have depleted B12 stores that require consideration when initiating treatment