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Females reported higher overall frequencies of poor appetite than males, whereas no significant sex differences were observed for insomnia, end-of-dose crash, or return of symptoms

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Unlike larger peptides, this small molecule can rapidly traverse the lipid bilayer of adipocytes to engage its intracellular target

[3] Nitric oxide is essential for mucosal defense: it maintains the gastric mucosal barrier and supports prostaglandin synthesis

Biol Chem 379:12011205 Arteel GE, Briviba K, Sies H (1999) Protection against peroxynitrite