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A more recent meta-analysis of randomized, controlled trials published in Obesity Research and Clinical Practice confirmed these findings, reporting that tesamorelin significantly reduced visceral fat, trunk fat, hepatic fat and waist circumference, while increasing lean body mass in adults with HIV-associated lipodystrophy

Its research profile is unusually broad for a single compound

Endothelial glycocalyx

This situation undermines the credibility of the reported outcomes and highlights the need for independent, peer-reviewed research

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