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Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells

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Sub q should in theory give close to 100% bioavailability, but we really dont know the one PK study never tested it, so theres no measured number and no dosing conversion behind it

Additionally, the potential for synergistic combination therapies (e.g., ferroptosis inhibitors + tolvaptan or ferroptosis inhibitors + mTOR inhibitors) is understudied

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However, clinical studies of the drug have focused on surgical patients