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It has been demonstrated that SC MTX is more clinically effective and has better tolerance than the oral route

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Urodynamics evaluation Under urethane anesthesia (20%, i.p.), rats underwent transurethral catheterization with PE-50 tubing connected to an infusion pump (6 mL/h saline) and pressure transducer for continuous intravesical pressure monitoring using BL New Century 2.1 software (Taimeng Technology, Chengdu, China) at 100 Hz sampling frequency, following a 30-min stabilization period to establish consistent voiding patterns