Gene regulation by transcription factors and microRNAs
IGF-1 expression has been shown to be activated by estrogens whereas breast tumors with BRCA1 mutations demonstrate elevated IGF-1 levels
Plant Cell Tissue Org Cult 108:1726 Jahan MS, Ogawa K, Nakamura Y, Shimoishi Y, Mori IC, Murata Y (2008) Deficient glutathione in guard cells facilitates abscisicacid-induced stomatal closure but does not affect light-induced stomatal opening
International Journal of Sport Nutrition and Exercise Metabolism, 30 (6), 405-411
Over the past 20 years there have been approximately 15 clinical trials targeting IGF in breast cancer listed as terminated or completed on the clinicaltrials.gov database
In a prospective population-based cohort of 643,757 COVID-19 patients, immunodeficiency, hypertension, diabetes, cardiovascular disease, chronic obstructive pulmonary disease (COPD), asthma, kidney disease, cerebrovascular disease, cirrhosis, dementia, severe obesity, and higher age were identified as factors that increased the risk of hospitalization (108)