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Since that COVID-19 exhibits unusual symptoms including GSH depletion, GPX4 inactivation, abnormal iron metabolism, and elevation of PUFA peroxidation by reactive oxygen species, it is possible that SARS-CoV-2 might cause ferroptosis in the dopaminergic neurons, which would then contribute to PD

However, evidence of clinically meaningful synergy remains limited, and no definitive conclusion can be drawn from current trials due to heterogeneity in design, population, and intervention protocols

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Melanin index, as measured by Mexameter, demonstrated a significant decrease by week 12 as compared to both pre-treatment baseline and control

d , OCR in gWAT and iWAT mitochondria of Control and Ndufs2 -KO mice at ZT14 in the presence of indicated substrates and inhibitors (n = 7 for gWAT and n = 6 for iWAT)