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The underlying mechanism involves the suppression of NF-B and STAT3 signaling pathways, which are crucial in the inflammatory response associated with PsO

4,7 The link between hearing loss and tinnitus has been suggested to be due to a compensatory effect: the brain compensates for decreased activation of the auditory nerve (which carries signals from the cochlea to the brain) by increasing gain or signal amplification in the auditory system of the brain, as well as decreasing auditory signal inhibition, which may result in tinnitus and possibly hypersensitivity to noise

Exosomes are cellular messengers that promote cell regeneration, improved circulation, and nerve repair

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Available from: [12] Celaj S, Kourkoumpetis T