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Glucose-6-phosphate dehydrogenase deficiency and stroke outcomes | Neurology

Clean the injection site with alcohol, allow to dry, pinch the skin lightly if needed, insert the needle at a 45 to 90 degree angle depending on tissue depth, and inject slowly

The activation of muscarinic receptors by Ach induces an increase in intracellular Ca 2+ concentration that activates calcium-activated chloride channels (CaCC) inducing also Cl secretion

The authors declare that no funds, grants, or other support were received during the present study

The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)