MK677 is often lumped in with peptides, but its actually a pill that acts like them
Bulletin of Experimental Biology and Medicine, 167 (5), 641-644
and people with an MTHFR genetic polymorphism (or mutation) whose cells are less efficient at converting folate into its active form
Things that might lead to dose changes include how bad the deficiency was, if there are nerve symptoms, if theres ongoing trouble absorbing nutrients, and how each patient responds
Some researchers even question whether the peptide has been correctly isolated, and whether it is actually produced by the body given the evidence for the gene that encodes it and receptors that interact with it are still scarce
Lower Risk of Growth-Related Side Effects: Because it does not appear to raise IGF-1 significantly, the peptide may carry fewer systemic risks than traditional growth hormone therapies