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So the first honest distinction is structural: tesamorelin is a modified full-length analog engineered for resistance to degradation, whereas sermorelin is an unmodified short fragment that reproduces GHRH activity but not GHRH stability

Rysz J, Gluba-Brzzka A, Franczyk B, Jabonowski Z, Ciakowska-Rysz A (2017) Novel biomarkers in the diagnosis of chronic kidney disease and the prediction of its outcome

The main difference between ipamorelin and GHRP-1 is that ipamorelin lacks the central dipeptide Ala-Trp [9]

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