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In summary, this experimental design combined pharmacological treatments, CRISPR-mediated receptor knockout, functional motility assays, protein-level detection, and transcript quantification to investigate the effects of Gepon and TGF-1 in fibroblasts

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Therefore, our study and published work collectively showed that FOXO4-DRI was able to remove senescent cells created by different methods

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The activity of eNOS is tightly regulated by multiple intracellular process including posttranslational modification, phosphorylation and proteinprotein interactions 14,15