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Atherosclerotic cardiovascular disease (ASCVD), including coronary heart disease, ischemic stroke, and peripheral arterial disease, accounts for a substantial portion of this global burden

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Glutathione is a tripeptide made up of three specific amino acids: cysteine, glycine, and glutamic acid

Translocation of phosphorylated-JNK (p-JNK) to the mitochondria enhances mitochondrial oxidative stress in mouse and humans (Xie et al., 2014