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Studies of topical use have reported improvements in skin density, thickness, and appearance of fine lines over 12-week windows, with a well-documented safety profile at typical cosmetic concentrations (Borkow, Using Copper to Improve the Well-Being of the Skin, 2015)

Given the positive effects in multiple animal models of aging and neurodegeneration, including models of AD, clinical trials for rapamycin in AD are underway (NCT04200911, NCT04629495)

Most patients see results the very next or second day after receiving their B12 shots, with improvements including boosted energy, clearer thoughts, and better sleep

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