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Pierson, T

The 2016 Noh investigation in International Journal of Molecular Sciences documented novel anti-melanogenesis properties of PDRN, identifying inhibition of microphthalmia-associated transcription factor (MITF) as the mechanism by which PDRN reduces melanin synthesis

The sequence reads across all samples achieved a mean sgRNA count of at least 546, with less than 2.2% of sgRNAs showing complete depletion (Supplementary Data 2)

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DeNicola et al, 2011