It exerts antioxidant, anti-inflammatory, antiaging, and chemopreventive activities affecting cellular signalling [205, 221, 222]
Topical numbing will be applied to the injection site
Oxidative stress is a potent, direct trigger for mast cell degranulation
Alpha Lipoic Acid is both fat- and water-soluble antioxidant that recycles glutathione, vitamin C and E
Aging (Reduced Synthesis Capacity) As you age, production of glutathione declines due to: Reduced activity of gamma-glutamylcysteine ligase (GCL) , the rate-limiting enzyme in glutathione synthesis Decreased cellular energy (ATP) to fuel glutathione recycling Lower levels of precursor amino acids (especially cysteine and glycine) Studies show glutathione levels drop 10-15% per decade after age 40 [3]
Exposure was accompanied by decreased cell viability, increased caspase 3 activity, and decreased intracellular GSH levels