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TABLE 1 The targeted molecular pathways of natural products in Alzheimers disease

Genetic ablation of PHGDH led to a phenotypic shift of M2 macrophages to M1, and antitumor T-cell mediated immunity against mesothelioma cells in a mouse model [116]

Through -glucuronidase activity, gut microbes deconjugate bound androgens, increasing circulating free testosterone levels ( Clinically, PCOS patients exhibit reduced gut microbial -diversity, an elevated Bacteroidetes-to-Firmicutes ratio, and decreased abundance of beneficial bacteria such as Akkermansia muciniphila

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