This interaction leads to intracellular accumulation of cholesterol in Tregs, along with increased fatty acid and cholesterol metabolism in mitochondria
doi:10.1002/mc.20741, PMID: 21319226 Yue P, Zhou Z, Khuri FR, Sun SY (2006) Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me)
2025;11:e41188
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Vitamin B3 (Niacin) Involved in energy metabolism, DNA repair, and cellular signaling, including pathways relevant to digestion and circulation