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A payload that has bystander activity can lose its bystander activity with a non-cleavable linker, which can also change the affinity of the payload to PGP pumps
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Its important to note that ordinary folic acid supplements do not have this ability high-dose leucovorin is needed to overcome the blockade [3]
Nutritional diseases and nutrient toxicities: A systematic review of the diets and nutrition for prevention and treatment
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