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249 Enhanced binding of MeCP2 to GAD1 and GAD2 promoters, which leads to reduced expression of RELN and mRNA, has been found in the cerebellum and frontal cortex in ASD patients

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The strength here lies in their ability to circumvent this fundamental bodily barrier

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This interaction is part of a coevolutionary relationship between hosts and microbes, with particular relevance to tryptophan-derived AhR ligands [50, 51]