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Safety and tolerability studies have generally found Sermorelin well-tolerated with fewer adverse effects than direct GH therapy, though injection site reactions, flushing, headache, and occasional dizziness can occur

Huang et al., 2012

Effectiveness of Compounded Bioidentical Hormone Replacement Therapy: An Observational Cohort Study

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AGE accumulation appears to impact collagen at the fiber and fibril levels, and conditions that induce excessive AGE formation are linked to negative tendon outcomes