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There is no direct trek between the two (like the one from Choquequirao to Vilcabamba, which is very advanced), but many do it as part of a longer trip through southern Peru

There are some very rare side effects listed in medical literature (mostly when large doses are given): for example, one out of many thousands of patients might develop a disturbance in liver enzymes or a tingling in the fingers or toes

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Patients with pre-existing peripheral neuropathy might report changes in sensation during treatment