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( G ) Indexing SLC7A11, as a critical regulator of intracellular GSH levels, to 15LO1 improves the relationship of 15LO1 to intracellular GSH ( n = 12)

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Senescent microglia may have a reduced capacity to modulate neuronal activity because of genetic changes that result in reduced surveillance, migration, and sensitivity to endogenous ligands, and a heightened sensitivity to pathogens, as seen in 24-month-old mice (Hickman et al., 2013

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