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Aging Pathobiology and Therapeutics (2022) 4

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A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment

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Evidence ranges from early laboratory work to clinical trials depending on the use the sections below cover the actual data and sources