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Of a particular interest, poly(lactide-co-glycolide) (PLGA) is a biocompatible and biodegradable polyester, which is used in several FDA-approved products in the form of microspheres and other pharmaceutical dosage forms 2,3

Pharmacol Ther 234:108117 Apostolova N, Gomez-Sucerquia LJ, Moran A, Alvarez A, Blas-Garcia A, Esplugues J (2010) Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells

Other peptides (BPC-157, GHK-Cu, Epitalon) have biological plausibility and animal data but lack human clinical validation

Increases in blood vessel constriction by COX-2 inhibition can also lead to the hypertension and renal failure seen in some studies of non-selective and COX-2 selective NSAIDs (Conaghan 2012)

And Joe Moore: yeah, Joe Moore: [00:28:00] thats it

de Oliveira, B