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PMID: 12170316

Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair

Among the enzymes contributing to the balance of the redox system, GSTP1/P2 catalyze the elimination of electrophilic oxidants

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By providing a robust intracellular antioxidant shield, glutathione helps stabilize hyper-reactive mast cells, making them less likely to release histamine in response to minor environmental triggers, thereby reducing the frequency of hives, flushing, and sudden allergic responses

Wang Y, Li Y, Liu Y, Zhang Y, Ke Z, Zhang Y, Liu Y (2021) Patients with IBD receiving methotrexate are at higher risk of liver injury compared with patients with non-IBD diseases: a meta-analysis and systematic review