FIGURE 3 Protection Against AQ-QI- and DEAQ-QI-Induced Apoptosis by GSTP1 To test whether AQ-QI and DEAQ-QI exposure induced apoptosis and to study the protective potential of GSTP1, activity of caspase 3 was measured under normal and GSH-depleted conditions ( Figure 4 )
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ROS production, lipid peroxidation, protein oxidation and DNA damage in RA patients are increased, and the activity of antioxidant defense system is decreased, resulting in oxidative stress (193)
doi:10.1016/j.nbd.2010.04.008
The role of antioxidants in the chemistry of oxidative stress: a review
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