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The unbalanced regulation of the glutathione synthesis coupled with the rapid and steady increase of glutathione abundance in the wheat tissue of the infested resistant plants suggested that the -glutamylcysteine synthetase might be either inhibited by a negative feedback from GSH, or it is not the rate-limiting enzyme in the glutathione synthetic pathway in wheat plants under our experimental conditions

Loren Pickart in 1973 [2]

In summary, although this study presents senotherapy as a promising alternative for enhancing anticancer strategies, numerous aspects of its application necessitate further investigation

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And some forms of degradation are completely invisible, which is why the BUD matters even when the solution looks fine

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