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Although a single dose of vitamin B-6 supplementation (50 mg/d) did not show a significant effect on the GSH and GSSG levels and activities of GSH-Px, GSH-Rd, and GSH-St in patients with hepatocellular carcinoma [14], the combination of vitamin B-6 and GSH supplementation are likely to have antioxidative effects in liver cirrhosis patients

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Compared to studies from other regions, some of these biomarkers showed similar expression patterns, while others differed importantly, likely reflecting genetic differences associated with continental ancestry across populations