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After the exchange of mitochondrial aspartate into the cytoplasm for glutamate, the aspartate is converted by GOT1 to oxaloacetate, which is reduced by malate dehydrogenase 1 (MDH1) back to malate with the concurrent oxidation of NADH

Oxidative stress and toxic exposure can deplete our livers ability to manufacture glutathione

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HRMC cells were cultivated in HG conditions, and HU effectively attenuated the HG-induced inflammation and apoptosis

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The experimental sample, QC sample, and standard were subjected to a derivatization reaction, and the resulting compounds were diluted in HM700 diluent and centrifuged at 12,000 g at 4 C for 10 min