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Laboratories studying cartilage matrix biology, chondrocyte proliferation and differentiation, and growth factor signalling in musculoskeletal research models have incorporated this fragment as an experimental variable representing an expanding research frontier beyond its primary metabolic applications

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The amino acid sequence is in the public domain and there is no composition-of-matter patent worth pursuing, so no commercial sponsor will fund the hundreds of millions a Phase IIIII development programme costs for a compound it cannot exclusively monetise